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The Oral Bioavailability of Trans‐Resveratrol from a Grapevine‐Shoot Extract in Healthy Humans is Significantly Increased by Micellar Solubilization  link
Hessian Business Development visits Darmstadt joint venture in Moscow Link
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (Basel, September 3rd - 7th, 2017)  link
Research on the positive effects of phytochemicals on the immune system  link
Rheinmaintv / IHK Darmstadt: Television coverage about AQUANOVA AG (german)  link
Hessen Trade & Invest: Technologie „Made in Hessen“ für russische Lebensmittel   link
Hessen-Nanotech: Technologie „Made in Hessen“ für russische Lebensmittel   link
Opening ceremony AQUANOVA RUS Oct. 23rd, 2015  link
Article about Curcumin research at University of Hohenheim with the title: "Spice with healing power" in German  link
Interview with Prof. Jan Frank from University of Hohenheim about his Curcumin research in German  link
Research NovaSOL® Curcumin rated #1 by Wiley  link
New Publication: Curcumin micelles improve mitochondrial function in a mouse model of alzheimer's disease
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New Publication: Photodynamic decontamination of foodstuff from Staphylococcus aureus based on novel formulations of curcumin
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NovaSOL® Curcumin presented in "The Curcumin Battleground"
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August 12th, 2014: AQUANOVA receives Technology Leadership Award 2014  link
"Novel strategies for the enhancement of the potency of nutraceuticals" (Curcumin): AQUANOVA participates in research sponsored by the German Federal Ministry of Education and Research.  link
 
you are here > TECHNOLOGY > RESEARCH PROJECTS

Research Projects

AQUANOVA continues to coloberate with scientific experts and research institutions. The following table gives a rough picture of the ongoing research projects.
 

Research objective

Active Component

Description

Antimicrobial Activity
 

NovaSOL® Curcumin

Wound healing in dentistry and dermatology / combat inflammatory diseases

Joint Health /
Joint disease (osteoarthritis)

NovaSOL® Curcumin
NovaSOL® Curcumin + Boswellia
NovaSOL® Curcumin + PS (Phoshatidylcholin)

Influence of curcumin (+ accompanying substance) in joint diseases and their prevention Comparison: curcumin, curcumin natively vs NovaSOL® Veterinary and possibly human study

Pharmacokinetics Oncology

NovaSOL® Curcumin

Light therapy and cancer (malignant melanoma and skin); Topic: effects and pharmacokinetics of native and mizelliertem curcumin combined with UVA and visible light - potential application in actinic keratosis

Oncology

NovaSOL® Curcumin

Technology development for better visualization of cancer growth without radiolabeling (Frauenhof institute of Leipzig and Oncotrition)

rheumatoid arthritis

NovaSOL® Curcumin

Investigation of the anti-destructive effect of curcumin NovaSOL in rheumatoid arthritis

Alzheimer

NovaSOL® Curcumin

human study

bowel disease

NovaSOL® Curcumin

Chronic inflammatory bowel disease and absorption of curcuminoids in the colon

dermatomycoses

NovaSOL® Curcumin

In vitro study of the antimicrobial effect of curcumin on pathogens of dermatomycoses

CaCo2 cells

NovaSOL® Curcumin

Caco2 cell experiments

CaCo2 cells

NovaSOL® Curcumin

Comparative study of the products of Wacker, Meriva and AQUANOVA by Caco2 cell experiments

Alzheimer / Australia

NovaSOL® Curcumin

Mouse Study: optical method for measuring the volume of the inflamed tissue, and verifying the memory performance of mice

Skin cancer /
malignant melanoma

NovaSOL® 6PN
(6-Prenylnaringenin)
NovaSOL® 8PN
(8-Prenylnaringenin)

Stimulation of natural killer cells in the cancer therapy of malignant melanoma; Implementing a human study

Skin cancer /
malignant melanoma

NovaSOL® Vineatrol®

3-5 Standardized cell lines
in vitro: Viability assays, cell cycle analysis, real-time cell monitoring, 3-D Hautrekonstrukte with immunohistochemistry
Vineatrol (commodity) / NovaSOL® Vineatrol / resveratrol (commodity) / Empty micelle

Vineatrol®: BV-study

NovaSOL® Vineatrol®
NovaSOL® Xanthohumol

Carrying out a comparative study with BV Vineatrol; further experiments with xanthohumol

sustainable Pharmacy

Paclitaxel (cytostatic)
17-alpha-Ethylestradiol (hormone)
Carbamazepine (antiepileptic)
Clarithromycin (antibiotic)

Bioavailability micellated drugs (cancer drug - Toxol / anti-inflammatory agent - cortisone / antibiotics - natamycin, macrolides) to CaCo2 cells, then animal studies (rats?); By improving the BV of not so good bioavailable drugs is less needed or given so much unused into the environment à environmental protection

Micelle analytics

generally

Developing a better micelle analytic

Rheumatoid arthritis / osteoarthritis

NovaSOL® Curcumin

Rheumatic diseases of children (and adults)